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Too much glutamate in the brain leads to excitotoxity, which can result in cell death, a loss of resilience to stress, depression, and other stress-related mental disorders

PubMed laboratory research record [PMID: 36691309] PubMed record related to this compound for laboratory literature review

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That would be expected, given that obesity and excess weight are risk factors for heart attack and stroke

Up-regulation of miR-133a-3p promotes ovary insulin resistance on granulosa cells of obese PCOS patients via inhibiting PI3K/AKT signaling

According to NICE guidance on type 2 diabetes management, regular monitoring and individualised treatment adjustments are essential to optimise outcomes whilst minimising adverse effects