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Pathway 4 - Exercise-Mimetic Signaling MOTS-c activates many of the same pathways as exercise: better endurance, better metabolic flexibility, more stress tolerance

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Furthermore, free radicals are generated by AGEs, resulting in an imbalance between free radicals and antioxidants in the body, which causes oxidative stress, tissue damage, and slow Wound Healing

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Its distinguishing characteristic is its lack of selectivity: it binds with high affinity to several melanocortin receptors simultaneously, MC1, MC3, MC4, and MC5

Kobayashi EH, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, et al