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Recent multi-omics analyses by Cappellani et al., for instance, have provided strong genetic and proteomic evidence linking DR pathogenesis directly to the activation of specific immune pathways, including the complement system and adaptive T-cell responses [53, 58, 59]
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GLP-1 binds to GLP-1 receptors, which are G-protein coupled receptors, found not only in the GI tract, but also in the pancreas, brain, and other tissues including the heart
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