keep weight off after glp 1 Did you hear about orforglipron, the new GLP-1 pill in the headlines this week? , A new randomised control trial, published in Nature Medicine (PMID: 42120723), explored the effects of this daily pill Some patients keep weight off

Local clinics are the right path if you want hands-on care, prefer in-person consultation, or have complex health needs that warrant a longer initial workup

Thirty-five years ago, in 1983, I was the first to introduce and bring l-carnitine to America from Japan as a supplement during my 27 years as Head of Product Development at Twinlab (1974-2001.) Today l-carnitine is an extremely popular supplement

Giblin K, Kaplan LM, Somers VK, Le Roux CW, Hunter DJ, et al

We have to differentiate between just wanting to lose weight without necessarily having a good medical reason to do so versus wanting to lose weight because of the health benefits. If your BMI is already normal, then youre probably not a candidate for GLP-1s

Ethics, consent and permissions All participants were informed orally and in writing and gave informed written consent before participation

For example, studies using radiolabeled exenatide have shown that it can readily enter the mouse brain, though this central uptake appears to diminish at higher doses (Kastin and Akerstrom, 2003)