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cefazolin) were believed to have a cross-reactivity rate of aroun d 10% in patients with a penicillin allergy [23]
The catalytic tetrad formed by Sec, glutamine, tryptophan and asparagine is essential for GPx activity, since these residues are crucial for enzyme-substrate interaction and stabilization of the GSH-GPx interaction [47, 65, 66]
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However, while GIPR agonism decreases body weight and food intake in a GLP-1R-independent manner via GABAergic GIPR + neurons, it remains unclear whether GIPR antagonism affects energy metabolism via a similar mechanism
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