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It modulates various signaling pathways, including those involving Nuclear Factor-kappa B (NF-B), a protein complex that plays a significant role in controlling DNA transcription and cell survival
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However, another randomized, double-blind, placebo-controlled trial in 181 patients with diabetic neuropathy found that oral supplementation with either 600 mg/day, 1,200 mg/day, or 1,800 mg/day of lipoic acid for five weeks significantly improved neuropathic symptoms (77)
Kynurenic acid: the Janus-faced role of an immunomodulatory tryptophan metabolite and its link to pathological conditions
National Library of Medicine
La consommation par voie orale ou topique peut aussi provoquer une ruption cutane et des irritations chez les enfants
