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Most of these events were mild to moderate and concentrated in the first four weeks of each dose escalation, meaning they tended to appear (and resolve) each time the dose increased

Several indirect mechanisms may explain why some patients report muscle pain or weakness while taking GLP-1 medications, even in the absence of direct myotoxicity

Figure 6 Mitochondrial Functional Markers There was no significant difference in MnSOD, Tom-20 and OXPHOS complexes among the three groups at P1 (Figures 7A,D,G)

Diabetes Obes Metab 20(5):12021212

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