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6 Conclusion and prospect ARDS is a heterogeneous syndrome, and different etiology, severity of symptoms, and individual genetic differences can bring about various clinical manifestations and responses to treatment

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This might involve increased dosing (up to 1000-1500mg per injection), enhanced frequency (moving from once weekly to twice or three times weekly), or strategic combination with synergistic supplements to amplify glutathione's effects

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This exacerbates lipid peroxidation, drives excessive ROS accumulation and neuroinflammation, and ultimately triggers ferroptosis, resulting in irreversible neuronal damage and neurotoxicity (Chen et al., 2025a)