Levothyroxine does not directly cause weight gain
Pharmacological stimulation of sigma-1 receptors has neurorestorative effects in experimental parkinsonism
Considerations for Linker Design of drug conjugates Drug Conjugate Linkers Effect on the PK, Efficacy, and Toxicity Profiles Hydrophilicity is crucial for the development of antibody-drug conjugates, and low hydrophilicity of the linker can cause many problems, such as low coupling efficiency, deposition of ADCs in plasma, and non-specific uptake of ADCs in tissues, and so on
[97] observed that liraglutide use was an independent negative predictor of LV mass index, suggesting liraglutide might prevent the progression of post-MI LV remodeling
Along these lines, an emerging theory linking excitotoxicity and mitochondrial dysfunction suggests that an accumulation of lactate, a metabolic byproduct which is toxic (especially to nerve cells) at high concentrations may play a role in ALS progression (Vadakkadath Meethal 2012)
CoolLipo Sculpting (Medical Fat Freezing) CoolLipo uses cryolipolysis technology to freeze targeted fat cells, and FDA-approved technique that causes fat cells to break down and be naturally eliminated
