Prospective, randomized trials are needed
This led to its use as an off-label treatment for obesity
Beyond dose changes, dietary modifications can help
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81 GPX1 decient mice develop normally but are more susceptible to lung inammation by inuenza infection or cigarette smoke exposure
Simultaneously, higher S-adenosylmethionine (SAM) availability supports key methylation-dependent pathways, which are crucial for epigenetic regulation and gene expression related to energy metabolism