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However, the treatment of NPC still faces great challenges due to chemoresistance [8]
S., Garzon, S., Casarin, J., Franchi, M., & Ghezzi, F
ODriscoll histological assessment Histological findings ( n = 8 at each time point) for each section were evaluated and scored by three investigators according to ODriscoll histological grading parameters (cell morphology, matrix staining, structural integrity, thickness/defect filling, osteochondral junction, adjacent bonding, basal integration, cellularity, clustering/distribution, and adjacent cartilage) to quantitatively evaluate the extent of cartilage repair based on the criteria of predominant tissue type, structural properties, freedom from degenerative changes in the neighboring cartilage, and freedom from cellular changes of degeneration [26]
Dosing for specific applications and populations While the standard protocols apply broadly, certain research contexts may benefit from adjusted approaches
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