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To facilitate the CEA, the NNT measures were only estimated for the statistically significant clinical outcomes between study groups: all-cause death (HR [95% CI]: 0.40 [0.18, 0.91]) and hospitalized hypoglycemia (0.43 [0.27, 0.69])

People with diabetes: The blood sugar-lowering effects of milk thistle may put people with diabetes at risk of low blood sugar

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Working with Your Healthcare Team If you're considering starting a GLP-1 medication or struggling with side effects: Be honest with your doctor about your symptoms Keep a symptom diary for a week or two Don't make major changes on your own work with your healthcare team Consider seeing a gastroenterologist if symptoms are severe or persistent Be patient it often takes a few months to find the right dose The Bottom Line GLP-1 medications can be powerful tools for managing diabetes and obesity, but digestive side effects are common