Generally I refer to both of these drugs as incretin medicines because they work to enhance natural gut hormones called incretins (GLP-1 and GIP)
GLP-1 RAs augment insulin secretion after meals and inhibit glucagon production from pancreatic alpha cells at hyper- or euglycemia
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Its immediate bioavailability can result in quicker and more pronounced effects, essential for medical situations requiring rapid response
For others, profound appetite suppression does not fully manifest until they reach higher doses during the titration process, which generally takes about four to eight weeks of consistent use
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