In addition, treatments with liraglutide, semaglutide, or tirzepatide were significantly associated with the occurrence of GLP-1 RA-related psychiatric AEs with relatively low ROR (ROR liraglutide = 0.88, 95% CI = 0.761.03, p = 0.0993
Apperloo EM, Neuen BL, Fletcher RA et al (2024) Efficacy and safety of SGLT2 inhibitors with and without glucagon-like peptide 1 receptor agonists: a SMART-C collaborative meta-analysis of randomised controlled trials
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Understanding the precise mechanism by which GLP-1 agonists work is essential when evaluating whether other compounds, such as berberine, share similar pharmacological properties
A proportion of participants in the retatrutide trial discontinued treatment due to gastrointestinal side effects that did not resolve