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Antagonists of neuronal calcium channels: structure, function, and therapeutic implications
Yellowing of the skin: In severe cases, B12 deficiency can affect the livers ability to process bilirubin, leading to jaundice and yellowing of the skin and eyes
Organoids derived from patient-specific induced pluripotent stem cells (iPSCs) now enable the in vitro modeling of various tissues, including the intestine, liver, and kidney
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Articular cartilage and joint health represent additional areas of therapeutic interest
Data availability The atomic coordinates and electron microscopy maps have been deposited in the Protein Data Bank (PDB) and Electron Microscopy Data Bank (EMDB) under accession codes: 9BP3/EMD-44760 [ (Cagri-AMY 1 R-DNG s complex), 9BLW/EMD-44678 [ (CagriBB-AMY 1 R-DNG s complex), 9BQ3/EMD-44796 [ (Cagri-AMY 2 R-DNG s complex), 9BTW]/EMD-44898 [ (Cagri-AMY 3 R-DNG s complex), 9BUB/EMD-44904 [ (Cagri-CTR-DNG s complex 1, bypass conformation), 9BUD/EMD-44906 [ (Cagri-CTR-DNG s complex 1, CT-like conformation), 9BUC/EMD-44905 [ (Cagri-CTR-DNG s complex 2, bypass conformation), 9BUE/EMD-44907 [ (Cagri-CTR-DNG s complex 2, CT-like conformation), 9BLC/EMD-44653 [ (CagriBB-CTR-DNG s complex 1, CT-like conformation), 9BLB/EMD-44652 [ (CagriBB-CTR-DNG s complex 1, bypass conformation)
