The exact ingredients can vary between brands, but GLP-1 patches typically contain a combination of natural extracts and vitamins , like: berberine (the main active ingredient, thought to support GLP-1 release) green tea extract cinnamon extract mint pomegranate extract a selection of vitamins None of these are clinically approved for weight loss , and the amounts absorbed through the skin are not well studied or proven to be effective
During your adjustment phase, focus on lean proteins like chicken and fish, low-sulfur vegetables such as spinach and green beans, and easily digestible carbs
4 weeks Minimum interval between dose increases 2mg to 12mg Phase 2 dose range (Jastreboff 2023) ~12 weeks Time to reach 12mg on standard protocol 24.2% Weight loss at 12mg, 48 weeks (Phase 2) Investigational Drug Warning Retatrutide (LY3437943) is not FDA-approved as of April 2026
Treatment with topical and systemic steroids led to recovery [57]
April 21, 2026
Dehvan F, Baghi V, Lotfi A, Ghanei Gheshlagh R