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The safety profile of topical GHK-Cu is well-established across decades of use and multiple clinical trials

42 The FIGHT trial, which enrolled patients hospitalised for acute decompensated HFrEF, showed no improvement with liraglutide on the primary composite endpoint of death, HF rehospitalisation or change in N-terminal pro B-type natriuretic peptide levels

Nature 388 , 482488 (1997)

Other researchers explored modifying the peptide backbone, such as replacing amino acids with a styrene moiety or reducing amide bonds

This article explores in detail the science behind this hypothesis and its practical implications

14 Glutathione deficiency 20 Impaired protein digestion may also be a limiting factor in ensuring healthy glutathione levels