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These findings suggest distinct renal phenotypes of responseliraglutide favoring albuminuria improvement and dulaglutide showing more stable filtration ratesunderscoring the potential for individualized selection based on predominant renal trajectory (proteinuria-dominant vs eGFR-decline phenotype)
The substantially reduced IGFBP affinity makes IGF-1 DES a precise tool for in vitro studies requiring direct IGF-1R activation without IGFBP-mediated sequestration confounding the experimental readout
Researchers said the ease of access raised red flags about patient safety
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