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International journal of molecular sciences 20 Stahli A, Maheen CU, Strauss FJ, Eick S, Sculean A, Gruber R (2019) Caffeic acid phenethyl ester protects against oxidative stress and dampens inflammation via heme oxygenase 1

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Historically, the brain has been considered an immune-privileged organ that is shielded from peripheral immune interactions by the bloodbrain barrier (BBB) [6]

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