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Preliminary pilot studies investigating semaglutide in people with AUD have reported early signals, with some participants experiencing reduced alcohol cravings and fewer heavy drinking days
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Researchers found a 9% reduction in biological aging speed using the DunedinPACE epigenetic clock, alongside improvements in markers linked to mortality risk and age-related disease
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Although the exact mechanism of action is not fully understood, it is hypothesised that bupropion stimulates hypothalamic pro-opiomelanocortin (POMC) cell, with downstream effects to reduce food intake and increase energy expenditure
It does not replace nutrition or exercise, but can complement a full wellness plan when levels are low
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