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Discontinuing an evidence-based IBD therapy like a biologic in favor of an unregulated peptide carries an exceptionally high risk of inducing a severe, uncontrolled disease flare that could lead to hospitalization or surgery
Expert Rev Clin Pharmacol (2016) 9:24165
A study in female patients with obesity who were prescribed a 925 kcal diet for 16 weeks followed by a 12001500 kcal diet for 32 weeks showed 11% weight loss in the first 2 months with reductions in triglycerides and total cholesterol by 22.7% and 15.7% respectively [29]
However, it contains no fillers or dyes and gets its colors from natural sources, such as beetroot powder
[1] [2] These contraindications are precautionary measures based on the rodent findings and the known genetic basis of these conditions
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