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The critical caveat: the formal FDA reclassification has been announced but not yet published in the Federal Register as of mid-March 2026
doi: 10.1002/jcph.940 93 SmitsMMTonneijckLMuskietMHAHoekstraTKramerMHHDiamantMet al
When prescribing GLP-1 receptor agonists, healthcare providers should consider the individual patients cancer risk profile and closely monitor for any signs of colorectal cancer
Hepatic fibrosis stage is the main predictor of liver-related morbidity and mortality: each unit increase in fibrosis stage confers a 2-fold increase in liver-related mortality and an approximately 1.5-fold increase in overall mortality [14]
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Key differences in storage sensitivity Both tirzepatide and semaglutide are acylated peptides with similar structural vulnerabilities to temperature extremes
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