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A 2023 World Health Organization (WHO) systematic review and guideline on non-sugar sweeteners cautioned against their long-term use for weight control, noting limitations in the evidence base

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Many users report nothing noticeable during this window, and that doesn't necessarily mean the compound isn't working senescent cell clearance is a biological process, not a feeling

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Mitchell KG, Bayley EM, Ikoma N, Antonoff MB, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG , Vaporciyan AA, Walsh GL, Maru DM, Erasmus JJ, Weston BR, Ajani JA, Badgwell BD, Hofstetter WL

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