This can make regaining weight after taking GLP-1s seem inevitable
Significant weight loss Semaglutide helps users achieve significant weight loss by mimicking the effects of endogenous GLP-1 to reduce hunger and food intake, as well as to maintain ideal body weight over time
The net result of the PPP, if not used solely for R5P production, is the oxidation of G6P, a six-carbon sugar, into a five-carbon sugar
By doing so, it becomes effective protection against obesity and insulin resistance that stems from the diet that one is taking or age
It would require somebody to use the agent continuously, and on top of that, the psychoactive effects during that time would preclude the use, especially in the guise that there are other agents that don't have these psychoactive effects or last longer and lower IOP better
Seizures due to GABA withdrawal (e.g., EtOH withdrawal)