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Source: Jastreboff et al., NEJM 2023 TRIUMPH-4 Phase 3 (68 weeks, 445 participants) Phase 2 Type 2 Diabetes Trial (36 weeks, 281 participants) In the type 2 diabetes population, weight loss was lower than in the obesity trial which is consistent with the pattern seen across all GLP-1 drugs
Gastrointestinal adaptation is common during the first month
P., Russo, C., Antic, T., Vacante, M., Malaguarnera, M., Avitabile, T., Li, Volti G., and Galvano, F
vitamin C, which is a required cofactor for collagen synthesis
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