Contraindications to GLP-1 Agonists: The No-Go Zones As with any blockbuster medication, there are some contraindications to be aware of when dispensing GLP-1 receptor agonists
Unclear understanding of the mechanism: There are ample amount of mechanistic studies delineating the role of CGRP's across different phases of migraine and drug receptor interactions and down stream effects
Mol Cell Endocrinol 515:110921 Pang Y, Yuan X, Guo J, Wang X, Yang M, Zhu J, Wang J (2019) The effect of liraglutide on the proliferation, migration, and osteogenic differentiation of human periodontal ligament cells
That change is easy to miss in the marketing materials but it meaningfully affects the monthly cost
2025 Jul 3;393(1):26-36
Which means you need to get it through nutrition and supplements