3.2 Biologic therapies (peptides, cytokine modulators, and cell-derived vesicles) 3.2.1 Mitochondria-targeted peptides and proteins We already mentioned SS-31 (elamipretide) which is technically a peptide (so it can be considered a biologic)
Exogenous human growth hormone (HGH) has decades of clinical research and multiple FDA-approved indications
Janiri, L., Martinotti, G., Tonioni, F., Ghelardini, C., Nicolai, R., Galeotti, N., Mosconi, L., Calvani, M., Bartolini, A., and Iannoni, E
Mol Biosyst 13:371379 Gibson EM, Monje M (2021) Microglia in cancer therapy-related cognitive impairment
This study was small and has not been replicated
From basic research to the bedside: efficacy of topical treatment with pseudocatalase PC-KUS in 71 children with vitiligo