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However, some molecules or drugs, such as erastin, sulfasalazine, sorafenib, and RSL3, are able to block glutathione synthesis or devitalize GPX4

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p125 Is a novel mammalian Sec23p-interacting protein with structural similarity to phospholipid-modifying proteins

, 16 , 1303-1314, doi: Nishizawa, S., Araki, H., Ishikawa, Y., Kitazawa, S., Hata, A., Soga, T., and Hara, T

The peptides very short half-life (3 minutes) means it does not accumulate in tissues over time, reducing concerns about long-term bioaccumulation