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While many compounds can force the growth of new blood vessels (angiogenesis), they often do so in a disorganized way that can lead to leaky vessels or unwanted tissue growth

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There are many driving factors in B12 deficiency including diet, vitamin B12 malabsorption from food, pernicious anemia, postsurgical malabsorption, and in many cases, the cause is unknown

This emphasizes the critical need for proper aseptic handling and storage to maintain sterility over repeated use