After switching to a lower dose and adding magnesium taurate, his symptoms improved
The most important GI symptom is constipation, which impacts almost 60% of people suffering with PD (Pavan et al., 2022)
doi: 10.1080/20002297.2025.2469896 57 FengX.WangY.ZhuC.HuaiQ.CuiJ
From 1987 to 1992, significant progress was made in cloning and characterizing the intestinal and renal SGLTs, leading to the development of selective SGLTis, known as gliflozins
GLP-1 receptor (GLP-1R) agonists modulate enteric immune responses through the intestinal intraepithelial lymphocyte (IEL) GLP-1R
Insulin secretion is stimulated, glucagon and gastric acid secretion are inhibited, and GI transit and motility are decreased by incretin hormones, especially glucagon-like peptide-1 (GLP-1), which is released postprandially from L-cells lining the gut in response to food ingestion (12)