Although these caspases cannot directly cleave the precursors of IL-1/IL-18, they can still trigger pyroptosis by cleaving GSDMD-NT, a process specifically activated by bacterial lipopolysaccharides [67, 68]
Even the relatively small amount of benzyl alcohol in bacteriostatic water can build up in neonates and cause a dangerous condition known as gasping syndrome, characterized by metabolic acidosis, gasping respiration, respiratory failure, and potentially fatal outcomes
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Regarding the form of vitamin B12 used, cyanocobalamin was the most common (n = 14), followed by methylcobalamin (n = 6), hydroxocobalamin (n = 4), and combinations including adenosylcobalamin in isolated cases
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