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AngIV-Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP/PS1 Mouse via the PI3K/AKT Signaling Pathway Sun X, Deng Y, Fu X, et al

Likewise, decreased gene expression of Egr was evident at 24 h in the inferior caval vein, Vegfr expression was decreased at 1 h and 24 h in all vessels, and Plc gene expression was decreased at 24 h in the inferior caval vein

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The downstream result is a significant reduction in pro-inflammatory cytokine release, including TNF-alpha, IL-1beta, IL-6, and IL-8, all of which are elevated in psoriatic skin