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Its activation of three key hormone receptors makes it distinct from other weight loss medications and capable of achieving significant weight loss through improved glucose, insulin, and fat metabolism regulation

Semaglutide GLP-1 and Wegovy were originally approved for the management of diabetes in overweight patients, but have now become approved for weight loss in overweight and obese patients

PMID 36242844

by Robert Kushner, MD Fall 2021 Disclaimer: Consult with your healthcare provider if you are interested in starting Wegovy

In a study involving 24 patients with inadequately controlled type 2 diabetes using metformin at baseline (mean HbA1c, 7.8%), sitagliptin or placebo was given on top of metformin for 12 weeks [37]

J Assoc Physicians India 2018;66:3740