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These sensations are normal and to be expected

Semaglutide, like its counterparts, can cause gastrointestinal issues, including nausea, vomiting, and diarrhea

Nonetheless, systematic reviews of regulatory studies provide great insight into the clinical impacts of semaglutide for weight management, summarized as follows [7, 12]

In rodents, this effect likely occurs through a calcitonin-dependent pathway since GLP-1 does not appear to have a direct effect on osteoblasts and osteoclasts in vitro [56]

Matyas, C., Hask, G., Liaudet, L., Trojnar, E

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