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Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation

GLP-1 is co-secreted with PYY 3-36 in response to nutrients in the gut, especially carbohydrates

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To ascertain that these effects were specific for Mdcs and not CAMs, cDC2s or microglia, we crossed Arg1 fl/fl mice with animals expressing the tamoxifen-inducible monocyte-specific Cre recombinase ( Ccr2 -Cre ER T2 ) 49 , generating Arg1 fl/fl Ccr2 -Cre ER T2 animals, and induced EAE in the presence of tamoxifen