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After exhaustive research efforts, GLP-1 was finally identified in 1986 [2]
12 The REWIND trial evaluated dulaglutide in a broader population, including those with a lower baseline cardiovascular risk, and demonstrated a significant reduction in composite cardiovascular outcomes, together with a favourable trend in HF-related events
Ozempic (semaglutide) is a glucagon-like peptide-1 receptor (GLP-1) agonist taken as a weekly injection thats approved by the Food and Drug Administration (FDA) to improve blood sugar control in adults with Type 2 diabetes, reduce the risk of stroke and heart attack in adults with Type 2 diabetes and cardiovascular disease, and help with slowing the progression of kidney disease in people with Type 2 diabetes and chronic kidney disease
Also a source of magnesium and healthy monounsaturated fats
In addition to this, DPP-4 inhibitors may increase the action of incretin hormones
It is important to note that retatrutide is not yet licensed in the UK, the US, or anywhere else in the world
