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Examination of their structures suggested different roles that phase II conjugation could play: either as detoxification, in concurrent, hence, competing with phase I oxidation, or as facilitating excretion, during the metabolism depending on the functional group a compound possesses

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Preventing HGF nitration-dysfunction could also improve the therapeutic effects of investigational HGF drugs for various diseases including liver cirrhosis, chronic renal failure, lung fibrosis, myocardial infarction, arteriosclerosis obliterans, amyotrophic lateral sclerosis (ALS, Lou Gehrigs disease), and acute spinal cord injury 47,48,49,50,51,52,53,54,55

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While this can provide short-term relief, prostaglandins play essential roles far beyond pain (27)

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