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Active lignans isolated from schisandra, particularly schisandrin A, appeared to reverse P-glycoprotein-mediated multidrug resistance of various cancer cell lines to doxorubicin, vincristine, and paclitaxel (20)
Johannes F.E
For example, in 2% albumin condition, the IC 50 is 5.39 when lipidation occurs at position 27, yet at position 26 it reaches 357
S.LeeseG.MacDonaldT
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This calls for more effective strategies to target protocol-based barriers to PRO implementation in interventional paediatric oncology trials
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