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H.MoochhalaS.NgY

10.1136/gutjnl-2015-311304 Gut

it consists of three key amino acids

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Mechanistically, E2F1-mediated CHAC1 upregulation promotes PKM2 SUMOylation enabling PKM2 nuclear translocation or kinase activation ( CHAC1s contribution to tumor progression is markedly influenced by the cellular and tumor context, differing across various cancer types