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doi: 10.1007/s10787-019-00618-0 167 RamonSBancosSSerhanCNPhippsRP

Excluded or Cautioned Populations in Phase 3 Trials Phase 3 REDEFINE/REIMAGINE protocols typically excluded participants with: Type 1 diabetes

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In a recent sham-controlled, randomised clinical trial of patients with refractory gastroparesis (41% had diabetes), G-POEM achieved symptomatic improvement in 71% of participants compared with 22% following the sham procedure [80]

It has no approved indication, no standardized dosing, and no manufacturer-backed clinical data