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They have similar effects, with even greater efficacy in weight-loss
a , GLP-1R (WT), b , GLP-1R triple mutant (L142A, K202A, Y145A), c , GLP-1R (K202A), d , GLP-1R (Y145A), e , GLP-1R (Y145F)
Additionally, patients should be monitored for signs of pancreatitis or severe allergic reactions
Phase 2 retatrutide data suggest ~2428% weight loss at 48 weeks
Dr Spreckley, who is leading AMPLIFY, said: These medications are transforming obesity care, but we know very little about how they shape peoples daily lives, including changes in appetite, eating patterns, wellbeing, and quality of life
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