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If you experience inadequate response after 1216 weeks at a therapeutic maintenance dose (typically 1015 mg weekly) despite good adherence and lifestyle modifications, consult your healthcare provider to assess for secondary causes, verify proper administration technique, and consider dose optimization or alternative treatment strategies

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They can also include related molecules, like nicotinamide riboside and nicotinamide mononucleotide

References Collins, Logan, and Ryan A Costello

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