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Expectations also play a large role
Mar 2020;222(3):251.e1-251.e10
Its used on demand rather than daily, so cumulative exposure is limited compared with maintenance medications
Rajakovich LJ, Fu B, Bollenbach M, Balskus EP Proceedings of the National Academy of Sciences of the United States of America 2021
A randomized ICU-based clinical trial by Yahyapoor, et al
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