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Another consideration is the impact of weight loss on thyroid hormone metabolism
Post-hoc analysis of SYNERGY-NASH trial reveals key insights on #tirzepatide in #MASH patients MASH resolution linked to greater weight loss (-16% vs -7%) Fibrosis improvement associated with better glycemic control Liver fat normalization was key mediator of both outcomes Weight reduction + metabolic improvements = disease modification potential in MASH To view or add a comment, sign in Advancing a first-in-class small molecule for MASLD (Metabolic dysfunctionAssociated Steatotic Liver Disease): Why MASLD matters: MASLD is the most common chronic liver disease, affecting around 35% of the global population
Pittler, M
A comprehensive metabolic panel (CMP) can assess kidney and liver function markers the two organ systems with the strongest preclinical evidence
This allows the medication to clear and metabolic signals to stabilize
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