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For those exploring solutions, a tummy tuck may offer a way to restore a smoother abdominal contour

Being aware if youve previously had conditions such as pancreatitis, gallbladder disease or liver enzyme changes is important, as these are uncommon yet significant risks

Several licensed weight management injectable therapies are available in the UK including semaglutide (Wegovy, approved by NICE for weight management in eligible adults) and tirzepatide (Mounjaro, licensed in the UK for type 2 diabetes and, subject to current NICE guidance, for weight management in eligible adults)

The practical takeaway is simple: tirzepatide may help lower blood pressure as part of a broader improvement in metabolic health, but it should not be viewed as a stand-alone hypertension treatment

Do not resume medication without explicit approval from your surgeon

Peer review Peer review information Nature Reviews Microbiology thanks Ellen Blaak, Hauke Smidt and the other, anonymous, reviewer(s) for their contribution to the peer review of this work