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This work represents one of the first demonstrations of FOXO4-DRI activity in primary human cells, supporting translational relevance beyond the initial mouse model findings

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3C and D, patients in the LGSH group exhibited significantly improved OS and DFS compared to those in the HGSH group (median OS: 70 months vs

CJC-1295 (with DAC) needs the fewest injections (weekly versus daily) but has no comparable trial evidence