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These drugs operate like semaglutide, replicating the physiological effects of GLP-1
Gastric inhibitory polypeptide immunoneutralization attenuates development of obesity in mice
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As a result, future obesity management is likely to prioritize integrated approaches that combine pharmacotherapy with lifestyle interventions, rather than replacing lifestyle changes with medication alone
This article reviews current evidence, evaluates pharmacological and mechanistic safety profiles, summarizes recent cohort studies, and discusses clinical management strategies for preconception counselling and inadvertent exposure
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