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Fatigue affects approximately 5-11% of patients taking these agents, according to FDA prescribing information
Who Should Avoid GLP-1 Medications Genetic and Cancer Concerns If you or your family has a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia type 2 (MEN 2), GLP-1 medications come with an increased risk of thyroid C-cell tumors and should be avoided
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At 11.2%, Retatrutide sees slightly more participants stopping treatment compared to Tirzepatides 9.1%
But its also possible that GLP-1 drugs have a direct therapeutic effect (for example, by reducing inflammation) that works independently of weight loss
Slightly slower progress preserves more lean mass
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