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IGF-1 DES Structure Sequence: TLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKAAKSA Molecular Formula: C 319 H 495 N 91 O 96 S 7 Molecular Weight: 7365.4225 g/mol PubChem CID: 135331146 CAS Number: 112603-35-7 Synonyms: Insulin-like growth factor 1, des-(1-3)-, Des(1-3) IGF-1, 4-70-insulin-like growth factor 1 IGF-1 DES Research IGF-1 DES Is More Potent Than IGF-1 IGF-1 DES is lacking just three amino acids from its N-terminal end, but that subtle change makes a big difference

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Similarly, by crossing BDNF +/ mice with APPdE9 mice (bearing APPswe and PSEN1E9 mutations), researchers found that while the haploinsufficiency-induced decrease of BDNF impaired learning and memory, it did not alter amyloid pathology [129]

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