Importantly, while incidence of IBD is still rising, the mortality is low and thus the prevalence of IBD escalates globally (Molodecky et al
Y.MesriM.et al
NICE guidance (NG145) recommends starting with a dose of 1.6 micrograms per kilogram of body weight per day in most adults, with lower starting doses (2550 micrograms daily) in older patients or those with cardiovascular disease
Given that VAT is among the depots reduced after treatment with exenatide or liraglutide, these regional changes in adipose tissue composition may help link GLP-1R agonists to adipose remodeling and enhanced cardioprotection
Zheng HJ, Guo J, Jia Q, Huang YS, Huang W-J, Zhang W, et al
And I think we just have to have that more nuanced take of they have benefits